Control of the type I interferon response by modifiers of lysine methylation

Chandwani R, Fang TC, Dewell S, Tarakhovsky A. Control of enhancer activation in the type I interferon response by the histone demethylase JMJD2d. Manuscript submitted for publication.

Fang TC, Schaefer U, Mecklenbrauker I, Stienen A, Dewell S, Chen MS, Rioja I, Parravicini V, Prinjha RK, Chandwani R, Macdonald MR, Lee K, Rice CM, Tarakhovsky A. Histone H3 lysine 9 di-methylation as an epigenetic signature of the interferon response. J Exp Med. 2012 Apr 9;209(4):661-9


Control of inflammatory responses by epigenetic reader proteins 

Nicodeme E, Jeffrey KL, Schaefer U, Beinke S, Dewell S, Chung CW, Chandwani R, Marazzi I, Wilson P, Coste H, White J, Kirilovsky J, Rice CM, Lora JM, Prinjha RK, Lee K, Tarakhovsky A. Suppression of inflammation by a synthetic histone mimic. Nature. 2010 Dec 23;468(7327):1119-23.


Other publications

Chandwani R, Ruda VM, Sehgal A, Bogorad RL, Akinc A, Charisse K, Tarakhovsky A, Novobrantseva TI, Koteliansky V. The roles of individual mammalian argonautes in RNA interference in vivo. PLoS One. 2014 Jul 3;9(7):e101749.

Chandwani R, D’Angelica MI. Intra-arterial chemotherapy for colorectal liver metastases. In E de Santibanes, M de Santibanes, V Ardiles, F Alvarez, VC Busnelli (Eds.) Extreme Hepatic Surgery and Other Strategies: Increasing Resectability in Colorectal Liver Metastases. (Springer: New York, NY, 2017).

Chandwani R, Jarnagin WR. Through & Through Duct-to-Mucosa Pancreaticojejunostomy. In M. Tewari (Ed.) How I Do It: Surgery for Pancreatic and Periampullary Cancer. (Springer: Singapore, 2017). 

Chandwani R, Allen PJ. Cystic neoplasms of the pancreas. Annu Rev Med. 2016 Jan 14;67:45-57.

Yang JS, Maurin T, Robine N, Rasmussen KD, Jeffrey KL, Chandwani R, Papapetrou EP, Sadelain M, O'Carroll D, Lai EC. Conserved vertebrate mir-451 provides a platform for Dicer-independent, Ago2-mediated microRNA biogenesis. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15163-8.

Gumbs AA, Duffy AJ, Chandwani R, Bell RL. Jejunojejunal anastomotic obstruction following laparoscopic Roux-en-Y gastric bypass due to non-absorbable suture: a report of seven cases. Obes Surg. 2006 Jan;16(1):12-5.

Chandwani R, Jordan KA, Shacklett BL, Nixon DF, Sandberg JK. Limited magnitude and breadth in the HLA-A2-restricted CD8 T cell response to Nef in children with vertically acquired HIV-1 infection. Scand J Immunol. 2004 Jan;59(1):109-14.

Ortiz GM, Hu J, Goldwitz JA, Chandwani R, Larrson M, Bhardwaj N, Bonhoeffer S, Ramratnam B, Zhang L, Markowitz MM, Nixon DF. Residual viral replication during antiretroviral therapy boosts human immunodeficiency virus type 1-specific CD8+ T-cell responses in subjects treated early after infection. J Virol. 2002 Jan;76(1):411-5.

Spiegel HM, Chandwani R, Sheehy ME, Dobrosyczki J, Fennelly G, Wiznia A, Radding J, Rigaud M, Pollack H, Borkowsky W, Rosenberg M, Nixon DF. The impact of early initiation of highly active antiretroviral therapy on the human immunodeficiency virus type 1-specific CD8 T cell response in children. J Infect Dis. 2000 Jul;182(1):88-95.